At a glance
ClinicalIndex Comparison RecordN/ACompleted· 228 enrolled
Drug / intervention
CCTA ~ BREAST SHIELDSradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The HEART BREAK Study: Effects of Heart Imaging Radiation on DNA Double-Stranded Breaks in Blood Lymphocytes and Hair Follicle Cells
In Brief
A clinical study evaluating CCTA ~ BREAST SHIELDS for Coronary Artery Disease and Chest Pain. Completed, enrolled 228 participants.
Detailed Summary
Purpose 1. To investigate the effects of cardiac imaging radiation on the induction of DNA double-strand breaks by enumerating gamma-H2AX foci in blood lymphocytes and plucked hair follicle cells. 2. To estimate whether the use of breast shields in cardiac computed tomographic angiography (CCTA) limits the effective radiation exposure of breast tissue.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCoronary Artery Disease, Chest Pain
Countries--
Collaborators--
Timeline
N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
Enrollment StartMar 2011
Primary CompletionSep 2015
First PostedDec 2015
Study CompletionDec 2015
TodayJul 2026
First PostedDec 1, 2015
Enrollment StartMar 1, 2011
Primary CompletionSep 1, 2015
Study CompletionDec 1, 2015
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 10.6 years ago
Interventions
CCTA ~ BREAST SHIELDSradiation
Breast shield placement (randomized) among women.