CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Bupivacaine Only +4 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02619409
NCT02619409N/ACompleted

Evaluation of the Duration of Bupivacaine Spinal Block as the Primary Anesthetic for Orthopedic Procedures With and Without Epinephrine Wash

Medical University of South Carolina·interventional·Posted Dec 2, 2015·Updated Jun 6, 2023

In Brief

A clinical study evaluating Bupivacaine Only, EPI25, and 3 other interventions for Arthropathy of Hip and Arthropathy of Knee. Completed, enrolled 30 participants across 1 site.

Detailed Summary

Bupivacaine spinal is commonly performed as the primary anesthetic for orthopedic procedures. In some cases the duration of the block is inadequate. An epinephrine wash is sometimes performed to prolong the duration of the block. The epinephrine wash may prolong the duration of the block, and if it does, to what extent?

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 2, 2015
Enrollment StartFeb 11, 2016
Primary CompletionOct 20, 2016
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 10.6 years ago

Interventions

Bupivacaine Onlydrug

The bupivacaine only group will receive bupivacaine 0.5% 3cc plus sterile saline 0.1cc.

EPI25drug

The EPI25 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.025cc, and sterile saline 0.075cc.

EPI50 groupdrug

The EPI50 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.05cc, and sterile saline 0.05cc

EPI75 groupdrug

The EPI75 group will receive bupivacaine 0.5% 3cc, epinephrine 1:1000 0.075cc, and sterile saline 0.025%.

EPI100 groupdrug

The EPI100 group will receive bupivacaine 0.5% 3cc, and epinephrine 1:1000 0.1cc.