At a glance
ClinicalIndex Comparison RecordEarly Ph 1Completed· 32 enrolled
Drug / intervention
Tretinoin +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
De Novo Lipogenesis of Sebaceous Glands in Acne
In Brief
A Early Phase 1 clinical trial evaluating Tretinoin and Isotretinoin for Acne Vulgaris. Completed, enrolled 32 participants across 2 sites.
Detailed Summary
There are two purposes of this study: 1. First, the investigators want to see what the differences are in de novo sebaceous lipid production of people with and without acne. 2. Secondly, the investigators want to know what happens to sebaceous gland de novo lipid production before and after treatment with topical tretinoin and oral isotretinoin.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcne Vulgaris
CountriesUnited States
Collaborators--
Timeline
Early Ph 1CompletedFinished
20162017201820192020202120222023202420252026
Enrollment StartOct 2015
First PostedDec 2015
Primary CompletionOct 2017
TodayJul 2026
First PostedDec 3, 2015
Enrollment StartOct 1, 2015
Primary CompletionOct 12, 2017
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 10.6 years ago
Interventions
Tretinoindrug
Subjects will apply 0.5% tretinoin cream nightly to their face for a total of 12 weeks.
Isotretinoindrug
Subjects will take isotretinoin as prescribed by their dermatologist.