CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 159 enrolled
Drug / intervention
IV acetaminophen + 0.5 mg IV hydromorphone +1 moredrug
Likely dose
IV acetaminophen + 0.5 mg IV hydromorphonefrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02621619
NCT02621619Phase 4Completed
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Randomized Clinical Trial of IV Acetaminophen as an Analgesic Adjunct to IV Hydromorphone in the Treatment of Acute Severe Pain in Elderly ED Patients

Montefiore Medical Center·interventional·Posted Dec 3, 2015·Updated Nov 8, 2018

In Brief

A Phase 4 clinical trial evaluating IV acetaminophen + 0.5 mg IV hydromorphone and Normal saline + 0.5 mg IV hydromorphone for Acute Pain. Completed, enrolled 159 participants across 1 site.

Detailed Summary

To determine the efficacy of intravenous (IV) acetaminophen as an analgesic adjunct to IV hydromorphone in the treatment of acute severe pain in the elderly Emergency Department (ED) patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcute Pain
CountriesUnited States
CollaboratorsNational Institute on Aging (NIA)

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 3, 2015
Enrollment StartMar 1, 2016
Primary CompletionOct 1, 2017
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 10.6 years ago

Interventions

IV acetaminophen + 0.5 mg IV hydromorphonedrug

1 gram (100 ml) IV acetaminophen in addition to 0.5 mg IV hydromorphone

Normal saline + 0.5 mg IV hydromorphonedrug

100 cc normal saline placebo in addition to 0.5 mg IV hydromorphone