CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 34,686 enrolled
Drug / intervention
More Frequent Surveillance Strategy +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02623712
NCT02623712N/ACompleted
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The Watch the Spot Trial: A Pragmatic Trial of More Versus Less Intensive Strategies for Active Surveillance of Patients With Small Pulmonary Nodules

Kaiser Permanente·interventional·Posted Dec 8, 2015·Updated Aug 14, 2025

In Brief

A clinical study evaluating More Frequent Surveillance Strategy and Less Frequent Surveillance Strategy for Solitary Pulmonary Nodule and 3 related conditions. Completed, enrolled 34,686 participants across 1 site.

Detailed Summary

This study will compare two clinically accepted protocols for surveillance imaging in individuals who are found to have a small pulmonary nodule on chest computed tomography (CT) scans.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSolitary Pulmonary Nodule, Coin Lesion, Pulmonary, Lung Neoplasms, Carcinoma, Non-small-cell Lung
CountriesUnited States
CollaboratorsPatient-Centered Outcomes Research Institute, University of California, Davis, University of California, San Francisco

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 8, 2015
Enrollment StartMar 6, 2017
Primary CompletionSep 4, 2024
TodayJul 2, 2026
Enrollment to primary: 7.5 yearsPosted 10.6 years ago

Interventions

More Frequent Surveillance Strategyother

Chest CT scans to be repeated at 3, 6, 12 and/or 24 months, depending on patient risk factors and nodule size and attenuation (density)

Less Frequent Surveillance Strategyother

Chest CT scans to be repeated at 3, 6, 12 and/or 24 months, depending on patient risk factors and nodule size and attenuation (density). Overall, participants in the less frequent arm are expected to undergo 30% fewer surveillance imaging tests.