CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 81 enrolled
Drug / intervention
Colchicine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02624180
NCT02624180Phase 2Completed

Inflammatory Pathogenesis of Coronary Atherosclerosis in HIV

Johns Hopkins University·interventional·Posted Dec 8, 2015·Updated Oct 21, 2021

In Brief

A Phase 2 clinical trial evaluating Colchicine and Placebo for Coronary Artery Disease and Human Immunodeficiency Virus. Completed, enrolled 81 participants across 1 site.

Detailed Summary

The investigators are studying whether an anti-inflammatory intervention improves impaired coronary endothelial function (CEF) in HIV+ people with no clinical coronary artery disease (CAD).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 8, 2015
Enrollment StartNov 1, 2015
Primary CompletionAug 1, 2020
Study CompletionSep 1, 2020
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 10.6 years ago

Interventions

Colchicinedrug

Administered to determine the effect of anti-inflammatory agents on coronary and systemic endothelial function in patients with coronary artery disease.

Placebodrug

A substance containing no medication