CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 27,034 enrolled
Drug / intervention
Propofol +37 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02625181
NCT02625181N/ACompleted
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Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis

Vanderbilt University·interventional·Posted Dec 9, 2015·Updated Mar 7, 2019

In Brief

A clinical study evaluating Automated recommendation at the start of the case, Automated notification at the start of surgery, and 36 other interventions for Postoperative Nausea and Vomiting. Completed, enrolled 27,034 participants across 1 site.

Detailed Summary

The purpose of this study is to determine how automated recommendations are best presented to optimize the adherence to guidelines on prophylaxis for nausea and vomiting after surgery.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPostoperative Nausea and Vomiting
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 9, 2015
Enrollment StartJul 1, 2016
Primary CompletionNov 2, 2017
Study CompletionNov 30, 2017
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 10.6 years ago

Interventions

Automated recommendation at the start of the caseprocedure

The first notification is the main notification that informs the anesthesia providers at the start of anesthesia of the risk score for that individual patient and the recommended number of prophylactic interventions. The notification occurs within the anesthesia information management system (AIMS)

Automated notification at the start of surgeryprocedure

The second notification within the AIMS will notify the anesthesia providers at the start of surgery when no prophylaxis has been given while three or more interventions were recommended.

Preoperative recommendations: by emailprocedure

A recommendation on PONV prophylaxis to anesthesia providers through email at the Vanderbilt University Medical Center.

Automated notification at the end of surgeryprocedure

A notification will remind anesthesia providers at the closing of surgery how many prophylactic interventions are required to adhere to the recommended number of interventions.

Anesthesia Information Management System (AIMS)device

The anesthesia electronic record keeping system

Perioperative Data Warehouse (PDW)device

The data warehouse that is used to gather perioperative data and create user reports. In this instance the PDW will be used to send the preoperative emails.

General anesthesiaprocedure

Any anesthetic drugs that are used to induce general anesthesia above the level of sedation.

Elective surgeryprocedure

Surgical procedures that are scheduled and not an emergency.

Propofoldrug

Anesthetic drug used to maintain general anesthesia

Sevofluranedrug

Anesthetic drug used to maintain general anesthesia

Isofluranedrug

Anesthetic drug used to maintain general anesthesia

Desfluranedrug

Anesthetic drug used to maintain general anesthesia

Scopolaminedrug

Prophylactic antiemetic

Droperidoldrug

Prophylactic antiemetic \& rescue antiemetic

Haloperidoldrug

Prophylactic antiemetic \& rescue antiemetic

Dexamethasonedrug

Prophylactic antiemetic \& rescue antiemetic

Promethazinedrug

Prophylactic antiemetic \& rescue antiemetic

Meclizinedrug

Prophylactic antiemetic \& rescue antiemetic

Aprepitantdrug

Prophylactic antiemetic \& rescue antiemetic

Metoclopramidedrug

Rescue antiemetic

Fentanyldrug

Analgesic drug / Opioid

Sufentanildrug

Analgesic drug / Opioid

Alfentanildrug

Analgesic drug / Opioid

Remifentanildrug

Analgesic drug / Opioid

Morphinedrug

Analgesic drug / Opioid

Meperidinedrug

Analgesic drug / Opioid

Hydromorphonedrug

Analgesic drug / Opioid

Methadonedrug

Analgesic drug / Opioid

Oxycodonedrug

Analgesic drug / Opioid

Oxymorphonedrug

Analgesic drug / Opioid

Hydrocodonedrug

Analgesic drug / Opioid

Ketaminedrug

Analgetic / Analgesic drug

Ondansetrondrug

Prophylactic antiemetic \& rescue antiemetic

Granisetrondrug

Prophylactic antiemetic \& rescue antiemetic

Dolasetron mesylatedrug

Prophylactic antiemetic \& rescue antiemetic

Palonosetrondrug

Prophylactic antiemetic \& rescue antiemetic

Tropisetrondrug

Prophylactic antiemetic \& rescue antiemetic

Ramosetrondrug

Prophylactic antiemetic \& rescue antiemetic