CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 40 enrolled
Drug / intervention
Optison +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02625428
NCT02625428Phase 4Completed
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Does Contrast-Enhanced Ultrasound Positively Influence Selection of Biopsy Sites When Evaluating Transplant Kidneys?

Mayo Clinic·interventional·Posted Dec 9, 2015·Updated Mar 2, 2020

In Brief

A Phase 4 clinical trial evaluating Optison, Ultrasound (US), and 1 other intervention for Transplantation, Kidney. Completed, enrolled 40 participants across 1 site.

Detailed Summary

This is a pilot study to investigate whether contrast-enhanced ultrasound (CEUS) may help evaluate segmental differences in renal perfusion better than Doppler Ultrasound and thus help direct the biopsy to the most abnormal part of the renal cortex. This should maximize detection and increase the odds of demonstrating the true grade/severity of the histopathological abnormality.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTransplantation, Kidney
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 9, 2015
Enrollment StartNov 1, 2015
Primary CompletionDec 1, 2018
Study CompletionDec 1, 2019
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 10.6 years ago

Interventions

Optisondrug

Ultrasound (US)other

A routine diagnostic and color-Doppler US. A Doppler ultrasound is a noninvasive test that can be used to estimate the blood flow through your blood vessels by bouncing high-frequency sound waves (ultrasound) off circulating red blood cells. A regular ultrasound uses sound waves to produce images, but can't show blood flow.

Contrast-enhanced ultrasound (CEUS)other

Contrast-enhanced ultrasound (CEUS) is the application of ultrasound contrast medium to traditional medical sonography. Ultrasound contrast agents rely on the different ways in which sound waves are reflected from interfaces between substances. This may be the surface of a small air bubble or a more complex structure.