CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 1,090 enrolled
Drug / intervention
Medical Management +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02627196
NCT02627196N/ACompleted

Barostim Neo® - Baroreflex Activation Therapy® for Heart Failure

CVRx, Inc.·interventional·Posted Dec 10, 2015·Updated Mar 10, 2026

In Brief

A clinical study evaluating BAROSTIM NEO® System and Medical Management for Heart Failure. Completed, enrolled 1,090 participants across 92 sites in 2 countries.

Detailed Summary

The purpose of this clinical trial (NCT02627196) is to develop valid scientific evidence for safety and effectiveness of Baroreflex Activation Therapy with the BAROSTIM NEO System in subjects with heart failure, defined as New York Heart Association (NYHA) functional Class III, left ventricular ejection fraction (LVEF) ≤ 35% and NT-proBNP\<1600 pg/ml despite being treated with the appropriate heart failure guideline directed therapy, excluding subjects eligible for or actively receiving Cardiac Resynchronization Therapy (CRT). The total trial duration is anticipated to be approximately 5 years; however, the duration of an individual subject enrollment will depend on when he or she entered the trial.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHeart Failure
CountriesUnited Kingdom, United States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 10, 2015
Enrollment StartApr 19, 2016
Primary CompletionOct 1, 2023
TodayJul 2, 2026
Enrollment to primary: 7.5 yearsPosted 10.6 years ago

Interventions

BAROSTIM NEO® Systemdevice

Medical Managementdrug