At a glance
ClinicalIndex Comparison Record- ✓Chronic stroke (>12 months post-stroke)
- ✓Single stroke only
- ✓Age ≥21 years, no upper limit
- ✓Severe hand/wrist motor deficit: unable to extend metacarpophalangeal joints ≥10° or wrist ≥20°
- ✕History of carpal tunnel syndrome or conditions causing peripheral neuropathy (diabetes, uremia, nutritional deficiency)
- ✕Head injury with loss of consciousness, severe alcohol/drug abuse, or psychiatric illness
- ✕Use within 3 months of recruitment of drugs known to impair motor recovery
- ✕Severe cognitive deficit precluding informed consent
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Enhancing Cortical Plasticity With Nerve Stimulation in Stroke Patients With Severe Motor Deficit
In Brief
A clinical study evaluating S88 Dual Output Stimulator by Grass Technologies for Stroke and Cerebrovascular Accident. Completed, enrolled 36 participants.
Detailed Summary
This study will evaluate the effectiveness of sustained peripheral nerve stimulation coupled with functional motor training, to improve hand motor function in poorly recovered stroke patients. The central hypothesis is that stroke patients with severe motor deficit receiving hand nerve stimulation and intensive task-oriented therapy will have improved motor function compared to patients receiving sham nerve stimulation and task-oriented therapy.
Study Details
Timeline
Interventions
Peripheral nerve stimulation of Erb's point, radial and median nerves paired with task-oriented therapy