CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 31 enrolled
Drug / intervention
Remote Ischemic Conditioning (RIC) +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02635347
NCT02635347N/ACompleted
CompareCT.gov

Remote Ischemic Conditioning (RIC) in Recipients of Brain Death Donor Livers - A Feasibility and Safety Study

Rutgers, The State University of New Jersey·interventional·Posted Dec 18, 2015·Updated Aug 20, 2019

In Brief

A clinical study evaluating Remote Ischemic Conditioning (RIC) and Pneumatic tourniquet for Liver Failure and Carcinoma, Hepatocellular. Completed, enrolled 31 participants across 1 site.

Detailed Summary

This study will assess the feasibility of lower limb-ischemia induced Remote Ischemic Conditioning (RIC) in the perioperative period before, during, and after Orthotopic Liver Transplantation (OLT). Remote ischemic conditioning will consist of 3 cycles of 5 minutes of lower limb ischemia induced via a mid-thigh pneumatic tourniquet, followed by 5 minutes of reperfusion. Interventions will take place after anesthesia induction but before surgery, at the completion of the procedure, and on the mornings of post-operative days 1-4.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLiver Failure, Carcinoma, Hepatocellular
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedDec 18, 2015
Enrollment StartNov 1, 2015
Primary CompletionOct 31, 2017
Study CompletionDec 31, 2017
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 10.5 years ago

Interventions

Remote Ischemic Conditioning (RIC)procedure

Each RIC intervention will comprise three cycles of 5 minutes of inflation followed by 5 minutes of deflation of a pneumatic tourniquet placed in mid-thigh.

Pneumatic tourniquetdevice

Portable Tourniquet System(PTSii, Delfi Medical Innovations, Inc.) used to perform RIC interventions.