At a glance
ClinicalIndex Comparison Record- ✓Elective cardiac surgery requiring cardiopulmonary bypass (CABG, valve replacement, or CABG + valve)
- ✕Emergency surgery
- ✕Extremes of age
- ✕Previous cardiac surgery
- ✕Clinical contraindications to succinylcholine or cisatracurium
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Prospective, Randomized Trial Comparing Effect of General Anesthesia With and Without Neuromuscular Blockade on Postoperative Pulmonary Complications in Elective Cardiac Surgical Patients
In Brief
A Phase 4 clinical trial evaluating Succinylcholine and Cisatracurium for Neuromuscular Blockade and Postoperative Complications. Completed, enrolled 100 participants across 1 site.
Detailed Summary
The investigators will conduct a prospective, randomized trial to assess the impact of neuromuscular blockade on early (\<72 hours post-ICU admission) postoperative respiratory complications in cardiac surgical patients. The study will compare continual neuromuscular blockade with cisatracurium to a single dose of succinylcholine during general anesthesia for cardiac surgery.
Study Details
Timeline
Interventions
Succinylcholine will be used to facilitate endotracheal intubation for general anesthesia in the operating room. No additional neuromuscular blockade will be provided during general anesthesia.
Cisatracurium will be used to maintain neuromuscular blockade during general anesthesia.