CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 90 enrolled
Drug / intervention
Regular Coffee +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02639728
NCT02639728N/ACompleted

Prospective Study of the Effect of Coffee Consumption in Enhancing Recovery of Bowel Function Following Colorectal Surgery.

Cedars-Sinai Medical Center·interventional·Posted Dec 24, 2015·Updated Nov 21, 2022

In Brief

A clinical study evaluating Regular Coffee, Decaffeinated coffee, and 1 other intervention for Postoperative Ileus. Completed, enrolled 90 participants across 1 site.

Detailed Summary

The effects of coffee have been shown to act as a colonic stimulant. Caffeinated coffee stimulates colonic activity, most notably in the transverse/descending colon, in magnitude similar to a meal, 60% stronger than water, and 23% stronger than decaffeinated coffee. \[1\] Moreover, the consumption of both water and caffeine causes a decrease in the rectal sensory threshold for the desire to defecate, while anal sphincter pressure after caffeine intake is significantly higher than after water intake. This may result in an earlier desire to defecate. \[2\] Coffee has also been shown to have an effect on defecation by increasing rectal tone by 45% (measured with a barostat) thirty minutes after consumption. \[3\]

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2014201520162017201820192020202120222023202420252026
First PostedDec 24, 2015
Enrollment StartNov 1, 2013
Primary CompletionMar 23, 2022
TodayJul 2, 2026
Enrollment to primary: 8.4 yearsPosted 10.5 years ago

Interventions

Regular Coffeeother

Regular coffee will be given a 4oz cup three times daily and will be instructed to consume all of its liquid contents.

Decaffeinated coffeeother

Decaffeinated coffee will be given a 4oz cup three times daily and will be instructed to consume all of its liquid contents.

Warm waterother

Warm water will be given a 4oz cup three times daily and will be instructed to consume all of its liquid contents.