At a glance

ClinicalIndex Comparison Record

Phase 4Completed· 110 enrolled

Drug / intervention

Oral Acetaminophen +1 moredrug

Likely dose

Oral Acetaminophen 1000mgfrom record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02643394

NCT02643394Phase 4Completed

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The Comparative Efficacy of Oral vs. Intravenous Acetaminophen in Sinus Surgery Patients

University of Texas Southwestern Medical Center·interventional·Posted Dec 31, 2015·Updated Apr 21, 2020

In Brief

A Phase 4 clinical trial evaluating Oral Acetaminophen and Intravenous acetaminophen for Postoperative Pain. Completed, enrolled 110 participants across 1 site.

Detailed Summary

The comparative efficacy of intravenous (IV) to oral (PO-'per os') acetaminophen in the management of postoperative pain is understudied and largely unknown. In this observer blinded randomized clinical trial, investigators aim to determine the comparative efficacy of PO (preoperative) vs. IV (intraoperative) acetaminophen in a sinus surgery population.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsPostoperative Pain

CountriesUnited States

Collaborators--

Timeline

Phase 4CompletedFinished

20162017201820192020202120222023202420252026

Enrollment StartAug 2015

First PostedDec 2015

Primary CompletionSep 2016

Study CompletionJan 2018

TodayJul 2026

First PostedDec 31, 2015

Enrollment StartAug 17, 2015

Primary CompletionSep 2, 2016

Study CompletionJan 15, 2018

TodayJul 2, 2026

Enrollment to primary: 1.0 yearsPosted 10.5 years ago

Interventions

Oral Acetaminophendrug

1000mg oral acetaminophen + 400mg oral celecoxib given within one hour of incision

Intravenous acetaminophendrug

400mg oral celecoxib given within one hour of incision + 1000mg IV acetaminophen within one hour prior to anesthetic emergence.