At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Blood Loss Reduction After Total Knee Arthroplasty. A Comparison Between Topical Tranexamic Acid and Platelet Rich Plasma: Controlled Clinical Trial
In Brief
A Phase 3 clinical trial evaluating Group 1 Tranexamic Acid and Group 2 Platelet rich plasma for Osteoarthritis. Completed, enrolled 40 participants across 1 site.
Detailed Summary
The investigators will include patients who will be schedule for total knee arthroplasty with a diagnosis of osteoarthritis. The patients will be divided in two groups. In both groups a verbal and clear detailed information will be given on the intraoperative approach. The first group will receive topical tranexamic acid and the second group topical platelet rich plasma; both in the surgical site. Both groups will be assessed before and after the intervention with laboratory results (hemoglobin, hematocrit levels) and drainage drain.
Study Details
Timeline
Interventions
2 gr of tranexamic acid will be applied on the surgical site.
16ml of platelet rich plasma will be applied of the surgical site