At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 15 enrolled
Drug / intervention
AZD7986 +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
An Open-label, Non-randomized, Fixed Sequence Study Assessing the Pharmacokinetics of AZD7986 When Administered Alone and With Multiple Doses of Verapamil and Itraconazole or Diltiazem in Healthy Subjects
In Brief
A Phase 1 clinical trial evaluating AZD7986, Verapamil, and 2 other interventions for Healthy Subjects. Completed, enrolled 15 participants across 1 site.
Detailed Summary
This is a phase 1, non-randomized, fixed sequence, 3-period, drug-drug interaction study to assess the pharmacokinetics (PK) of AZD7986 in healthy subjects when administered alone and in combination with multiple doses of verapamil and itraconazole or diltiazem
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy Subjects
CountriesUnited Kingdom
Collaborators--
Timeline
Phase 1CompletedFinished
20162017201820192020202120222023202420252026
First PostedJan 2016
Enrollment StartJan 2016
Primary CompletionApr 2016
TodayJul 2026
First PostedJan 12, 2016
Enrollment StartJan 22, 2016
Primary CompletionApr 13, 2016
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 10.5 years ago
Interventions
AZD7986drug
Oral solution, single dose, dilution from concentrate
Verapamildrug
Extended release tablet for oral use
Itraconazoledrug
Oral solution
Diltiazemdrug
Extended release capsule