CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 59 enrolled
Drug / intervention
Cognitive Remediation Trainingbehavioral
Likely dose
Cognitive Remediation Training: up to 65 hours of computer-based cognitive trainingAI-extracted
Key inclusion· 3
  • Primary diagnosis of alcohol use disorder (AUD)
  • Within 30 days of detoxification or last use at time of recruitment
  • Enrolled in VA AUD treatment (veterans) or AUD treatment program (non-veterans)
Key exclusion· 3
  • Other medical illnesses that compromise neurocognition
  • Active use of prescribed opioids or benzodiazepines that may hinder new learning
  • Pending incarceration or plans to leave the state

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02664038
NCT02664038N/ACompleted

Cognitive Training in the Treatment of Alcohol Use Disorders in Older Veterans

VA Office of Research and Development·interventional·Posted Jan 26, 2016·Updated Aug 27, 2024

In Brief

A clinical study evaluating Cognitive Remediation Training for Alcohol Use Disorder Cognitive Decline. Completed, enrolled 59 participants across 1 site.

Detailed Summary

Alcohol Use Disorders (AUDs) have a significant public health impact and are highly prevalent in Veterans. Alcohol related brain effects on neurocognition (attention, memory and executive function) reduce ability to benefit from current treatments. These cognitive impairments are especially common in the early phase of recovery, persist over years and get worse with age. Recent research suggests that cognitive remediation therapy (CRT) may improve attention, memory and executive function in other disorders, and the investigators just completed pilot study with AUD Veterans found significantly greater improvements for those receiving CRT. The proposed study examines AUD outcomes and neurocognitive improvements when CRT is combined with a standardized alcohol treatment. The investigators hypothesize that CRT will improve neurocognition and AUD outcomes more than standardized alcohol treatment alone. Findings will determine whether CRT augmentation can benefit Veterans with AUDs.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedJan 26, 2016
Enrollment StartAug 22, 2016
Primary CompletionSep 30, 2021
Study CompletionJun 30, 2022
TodayJul 2, 2026
Enrollment to primary: 5.1 yearsPosted 10.4 years ago

Interventions

Cognitive Remediation Trainingbehavioral

Up to 65 hours of computer based cognitive training of attention, verbal and visual memory, verbal and visual working memory, and executive functions