CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 61 enrolled
Drug / intervention
Plaque identifying toothpaste +1 moreother
Likely dose
Not stated in record
Key inclusion· 5
  • Age 19-45 years
  • All 12 anterior teeth present (canine to canine in both upper and lower arches)
  • Apparently healthy with no history of cardiovascular disease
  • English speaking
Key exclusion· 12
  • Taking aspirin, NSAIDs, or statins
  • Pregnant or nursing women
  • Women taking birth control pills or using hormone-releasing contraceptive devices
  • Women on hormone replacement therapy

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02666508
NCT02666508N/ACompleted

A Randomized Trial of Plaque Identifying Toothpaste on Reduction of Plaque and Inflammation

University of Illinois at Chicago·interventional·Posted Jan 28, 2016·Updated Jan 14, 2021

In Brief

A clinical study evaluating Plaque identifying toothpaste and Non-plaque identifying toothpaste for Plaque and Inflammation. Completed, enrolled 61 participants across 1 site.

Detailed Summary

Dental plaque causes caries and periodontal disease and data are sparse about toothpaste and plaque removal. Inflammation, caused by dental plaque, is a risk factor for cardiovascular disease. (CVD) The availability of (Plaque HD (TM), a plaque identifying toothpaste with targetol technology (TM)), afforded the unique opportunity to test whether there were statistically significant and clinically important reductions in plaque and inflammation in a randomized trial of apparently healthy individuals.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPlaque, Inflammation
CountriesUnited States

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedJan 28, 2016
Enrollment StartSep 1, 2015
Primary CompletionApr 1, 2016
Study CompletionAug 22, 2016
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 10.4 years ago

Interventions

Plaque identifying toothpasteother

Plaque identifying toothpaste with targetol

Non-plaque identifying toothpasteother

Non-plaque identifying toothpaste without targetol