At a glance
ClinicalIndex Comparison RecordN/ACompleted· 50 enrolled
Drug / intervention
Epidural bupivacaine with vasoconstrictor 0.125% +6 moredrug
Likely dose
Epidural bupivacaine with vasoconstrictor 0.125% 10 mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Plasmatic Catecholamines After Neuraxial Labor Analgesia: a Randomized Controlled Trial Comparing Epidural Versus Combined Spinal-epidural
In Brief
A clinical study evaluating Epidural bupivacaine with vasoconstrictor 0.125%, Epidural sufentanil, and 5 other interventions for Fetal Bradycardia and 2 related conditions. Completed, enrolled 50 participants across 1 site.
Detailed Summary
Combined spinal-epidural (CSE) for labor analgesia has been associated with fetal bradycardia and uterine hypertonia, possibly due to asymmetric decrease in catecholamine levels, when compared with epidural analgesia (EP).
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFetal Bradycardia, Hypertonic Uterine, Catecholamines
CountriesBrazil
Collaborators--
Timeline
N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedJan 2016
Enrollment StartJul 2017
Primary CompletionOct 2020
TodayJul 2026
First PostedJan 28, 2016
Enrollment StartJul 12, 2017
Primary CompletionOct 16, 2020
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 10.4 years ago
Interventions
Epidural bupivacaine with vasoconstrictor 0.125%drug
10 ml
Epidural sufentanildrug
20 mcg
Placement of the epidural catheterprocedure
Placement of the epidural catheter
Intrathecal hyperbaric bupivacaine solution 0.5%drug
2.5 mg
Intrathecal morphinedrug
60 mcg
Placement of an epidural catheter to the catheter through technical needleprocedure
Placement of an epidural catheter to the catheter through technical needle
Intrathecal sufentanildrug
5 mcg