CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 20 enrolled
Drug / intervention
Head positions and spinal manipulationother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02667821
NCT02667821N/ACompleted
CompareCT.gov

Changes in Vertebral Artery and Cerebral Hemodynamics Following Various Head Positions & Cervical Manipulation in Patients With Chronic/Recurrent Neck Pain

Canadian Memorial Chiropractic College·interventional·Posted Jan 29, 2016·Updated Oct 10, 2017

In Brief

A clinical study evaluating Head positions and spinal manipulation for Vertebral Artery Dissection and 2 related conditions. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The Investigators are performing a study to determine, in patients with chronic/recurrent neck pain, the cerebrovascular hemodynamic consequences of cervical spine movements, including manipulation, in vivo using fMRI technology on vertebral and cranial blood flow dynamics affecting brain perfusion, and extend the current data set on these variables

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsVertebral Artery Dissection, Cerebrovascular Accident, Stroke
CountriesCanada
CollaboratorsNational Chiropractic Mutual Insurance Company (NCMIC)

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedJan 29, 2016
Enrollment StartJun 1, 2016
Primary CompletionMay 1, 2017
TodayJul 2, 2026
Enrollment to primary: 11 monthsPosted 10.4 years ago

Interventions

Head positions and spinal manipulationother

Each participant will undergo three separate test maneuvers. Neutral (0° rotation) neck position (condition 1) will be followed by block randomization between maximum voluntary rotation (condition 2) and a high-velocity-low-amplitude cervical manipulation targeted at C1-C2 (condition 3). Conditions 1 and 2 will be held for 1 minute before returning to neutral alignment. For the manipulation, the head will be repositioned at neutrality immediate. An experienced practitioner will perform the manipulation on the adjustable and pivotal MRI bed. After each condition, MRI of the upper neck and cerebrum for perfusion and blood flow will ensue.