CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 338 enrolled
Drug / intervention
Leukemia Profilinggenetic
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02670525
NCT02670525N/AActive

Matched Targeted Therapy (MTT) Recommendation for Patients With Recurrent, Refractory, or High Risk Leukemias and Myelodysplastic Syndrome

Dana-Farber Cancer Institute·interventional·Posted Feb 1, 2016·Updated Jan 9, 2026

In Brief

A clinical study evaluating Leukemia Profiling for Recurrent, Refractory, or High Risk Leukemias and Matched Targeted Therapy. Active but no longer recruiting, targeting 338 participants across 15 sites.

Detailed Summary

This research study is seeking to gain new knowledge about Recurrent, Refractory, or High Risk Leukemias in children and young adults. This study is evaluating the use of specialized testing called leukemia profiling. Once the profiling is performed, the results are evaluated by an expert panel of physicians, scientists and pharmacists. This may result in a recommendation for a specific cancer therapy or a clinical trial called matched targeted therapy (MTT). The results of the leukemia profiling and, if applicable, the MTT recommendation will be communicated to the participant's primary oncologist.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/AActive
2016201720182019202020212022202320242025202620272028
First PostedFeb 1, 2016
Enrollment StartAug 17, 2016
Primary CompletionMay 16, 2022
Study CompletionJan 31, 2028
TodayJul 2, 2026
Enrollment to primary: 5.7 yearsPosted 10.4 years ago

Interventions

Leukemia Profilinggenetic

Genetic profiling of leukemia cells will be performed and analyzed by an expert panel. Matched targeted therapy recommendation based on profiling results will be made if available. The recommendation, if available, will be communicated to the primary oncologist.