CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 29 enrolled
Drug / intervention
ATB200 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02675465
NCT02675465Phase 2Completed

An Open-Label, Fixed-Sequence, Ascending-Dose, First-in-Human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of Intravenous Infusions of ATB200 Co-Administered With Oral AT2221 in Adult Subjects With Pompe Disease

Amicus Therapeutics·interventional·Posted Feb 5, 2016·Updated Oct 23, 2025

In Brief

A Phase 2 clinical trial evaluating ATB200 and AT2221 for Pompe Disease. Completed, enrolled 29 participants across 19 sites in 6 countries.

Detailed Summary

This is an international, multi-center, open-label study designed to evaluate if the co-administration of investigational new drugs ATB200 and AT2221 is safe in adults with Pompe disease.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPompe Disease
CountriesAustralia, Germany, Netherlands, New Zealand, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedFeb 5, 2016
Enrollment StartApr 1, 2016
Primary CompletionAug 22, 2024
TodayJul 2, 2026
Enrollment to primary: 8.4 yearsPosted 10.4 years ago

Interventions

ATB200drug

AT2221drug