At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized, Placebo-Controlled, Double-Blind, Two-Part, Cross-over Study in Healthy Adult Male Subjects to Compare the Reduction in Pain Intensity After Single-Dose Administration of Intravenous or Oral Acetaminophen and Intravenous Morphine by Using UVB Burn and Intradermal Capsaicin Experimental Pain Models
In Brief
A Phase 4 clinical trial evaluating IV Acetaminophen (Treatment A), Oral Acetaminophen (Treatment B), and 2 other interventions for Pain. Completed, enrolled 79 participants across 1 site.
Detailed Summary
The purpose of this study is to evaluate two experimental pain models to see if they would be useful for comparing different products for reduction in pain intensity. The models evaluated were the ultraviolet-B (UVB) burn and intradermal capsaicin experimental pain models. Medications compared were a single dose each, of intravenous (IV) acetaminophen, oral acetaminophen, placebo, and IV morphine.
Study Details
Timeline
Interventions
Acetaminophen administered by intravenous (IV) infusion
Acetaminophen administered by oral tablets
Placebo administered by IV infusion or oral tablets
Morphine administered by IV infusion