CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 44 enrolled
Drug / intervention
Handihaler-Tiotropium 18 mcg untrained +2 morecombination
Likely dose
Handihaler-Tiotropium 18 mcg untrainedfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02683668
NCT02683668Phase 3Completed

Targeting of the Small Airways in Patients With COPD: Airway Effects of Tiotropium - Respimat vs Handihaler

Imperial College London·interventional·Posted Feb 17, 2016·Updated Aug 29, 2025

In Brief

A Phase 3 clinical trial evaluating Handihaler-Tiotropium 18 mcg untrained, Handihaler-Tiotropium 18 mcg trained, and 1 other intervention for COPD and LUNG DISEASES, OBSTRUCTIVE. Completed, enrolled 44 participants across 1 site.

Detailed Summary

The aim of the study is to investigate the effect of tiotropium from different devices on a panel of small (IOS, MBNW, DLCO, FVC) and large airway (FEV1, PEF) responses in patients with mild-moderate COPD. Comparisons will be made between Tiotropium Handihaler 18 micrograms once daily and Tiotropium Respimat 5 micrograms once daily

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom

Timeline

Phase 3CompletedFinished
20162017201820192020202120222023202420252026
First PostedFeb 17, 2016
Enrollment StartFeb 1, 2016
Primary CompletionJan 1, 2018
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 10.4 years ago

Interventions

Handihaler-Tiotropium 18 mcg untrainedcombination

We are looking at the untrained used of Handihaler

Handihaler-Tiotropium 18 mcg trainedcombination

We are looking at the trained use of Handihaler after 14 days treatment

Respimat-Tiotropium 5 mcg trainedcombination

we are looking at the trained use of Respimat after 14 days treatment