At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 60 enrolled
Drug / intervention
propofol postconditioning +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function in Patients Undergoing Intracranial Aneurysm Surgery.
The Third Central Clinical College of Tianjin Medical University·interventional·Posted Feb 25, 2016·Updated Jul 11, 2017
In Brief
A Phase 4 clinical trial evaluating propofol postconditioning and sevoflurane for Cerebral Arterial Aneurysm. Completed, enrolled 60 participants.
Detailed Summary
The purpose of this study was to evaluate differences between propofol postconditioning and sevoflurane anesthesia in the intracranial aneurysm surgery about antioxidant effect.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCerebral Arterial Aneurysm
Countries--
Collaborators--
Timeline
Phase 4CompletedFinished
201520162017201820192020202120222023202420252026
Enrollment StartJul 2014
Primary CompletionDec 2015
Study CompletionJan 2016
First PostedFeb 2016
TodayJul 2026
First PostedFeb 25, 2016
Enrollment StartJul 1, 2014
Primary CompletionDec 1, 2015
Study CompletionJan 1, 2016
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 10.4 years ago
Interventions
propofol postconditioningdrug
administrated Target Controlled Infusion(TCI) of propofol (Cp 1.2ug/ml) and decreased sevoflurane with a Bispectral index (BIS) value of 40-60 to maintain anesthesia after clamp removal
sevofluranedrug
0.5%-2% sevoflurane with BIS 40-60