CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 15 enrolled
Drug / intervention
Blue blocking (BB) lenses +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02698800
NCT02698800N/ACompleted

Blocking Nocturnal Blue Light to Treat Insomnia: A Pilot Randomized Controlled Trial

Columbia University·interventional·Posted Mar 4, 2016·Updated Jul 30, 2019

In Brief

A clinical study evaluating Blue blocking (BB) lenses and Clear lenses for Insomnia and Sleep. Completed, enrolled 15 participants across 1 site.

Detailed Summary

Under entrained conditions, humans maintain a consolidated nocturnal sleep episode that coincides with environmental darkness and endogenous melatonin secretion. Various factors, such as artificial light, can compromise this temporal harmony, resulting in sleep disruption. Light is the strongest synchronizer of the circadian clock, with direct inputs via the retinohypothalamic tract to brain centers regulating sleep and circadian rhythms. Evening light exposure can suppress melatonin secretion and worsen sleep. This is critical, since most individuals routinely expose themselves to light before bedtime. The high sensitivity of the circadian system to blue wavelength light indicates that modern light sources such as light-emitting diodes (LED) may have particularly deleterious effects on sleep. It is possible to selectively filter out blue light while maintaining other visible spectra with blue-blocking (BB) lenses. Wearing BB lenses before bedtime may present a simple, affordable, and safe method to improve sleep. None have yet investigated the effects of BB lenses on subjective and objective sleep in insomnia patients, while simultaneously exploring the effects on melatonin secretion.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInsomnia, Sleep
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedMar 4, 2016
Enrollment StartMar 1, 2016
Primary CompletionMar 1, 2017
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 10.3 years ago

Interventions

Blue blocking (BB) lensesdevice

Participants will wear blue blocking lenses each night for 1 week for 2 hours preceding bedtime.

Clear lensesdevice

Participants will wear clear lenses each night for 1 week for 2 hours preceding bedtime.