CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 282 enrolled
Drug / intervention
BCT197 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02700919
NCT02700919Phase 2Completed

A Phase II, Two-Part, Randomised, Multi-Centre, Multinational, Double-Blind, Placebo-Controlled, Parallel Group Study to Compare the Efficacy and Safety of BCT197 When Added on to Standard of Care for the Treatment of Acute Respiratory Exacerbations of Chronic Obstructive Pulmonary Disease Requiring Hospitalisation in Adults

Mereo BioPharma·interventional·Posted Mar 7, 2016·Updated Nov 30, 2020

In Brief

A Phase 2 clinical trial evaluating BCT197 and Placebo for Pulmonary Disease, Chronic Obstructive. Completed, enrolled 282 participants across 46 sites in 10 countries.

Detailed Summary

The purpose of this study is to compare the efficacy and safety of BCT197 when added on to standard of care in adult subjects with acute respiratory exacerbations of chronic obstructive pulmonary disease requiring hospitalization. Additionally, the study will characterize the pharmacokinetics of BCT197 in adults with COPD. The total duration of the study will be 26 weeks. Subjects will receive study treatment administration over a period of 5 days after randomization. It is expected that approximately 255 subjects will complete the study and follow-up.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBulgaria, Czechia, Germany, Hungary, Italy, Latvia, Poland, Romania, Russia, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedMar 7, 2016
Enrollment StartAug 1, 2016
Primary CompletionNov 8, 2017
Study CompletionNov 28, 2017
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 10.3 years ago

Interventions

BCT197drug

Capsules will be taken orally with fluids over a 5 day period after randomization

Placebodrug

Capsules will be taken orally with fluids over a 5 day period after randomization