CI

At a glance

ClinicalIndex Comparison Record
N/ARecruiting· 51 target
Drug / intervention
Conventional Surgery +3 moreprocedure
Likely dose
Not stated in record
Key inclusion· 6
  • ✓Histologically confirmed soft tissue sarcoma of extremity or trunk
  • ✓Intermediate or high grade sarcoma
  • ✓Resectable primary lesion, including those with pre-existing metastasis if primary will be resected
  • ✓Recurrent disease of any grade, with no previous radiation therapy
Key exclusion· 3
  • ✕Active treatment of a separate malignancy
  • ✕History of prior irradiation to the area to be treated
  • ✕Pre-operative chemotherapy

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02701153
NCT02701153N/ARecruitingOn TrackUpdated 3mo ago
Long Recruiting
CompareCT.gov

Phase II Study of 5-Day Hypofractionated Preoperative Radiation Therapy for Soft Tissue Sarcomas: Expansion Cohort

Jonsson Comprehensive Cancer Center·interventional·Posted Mar 8, 2016·Updated Mar 10, 2026

In Brief

A clinical study evaluating Conventional Surgery, Hypofractionated Radiation Therapy, and 2 other interventions for Recurrent Adult Soft Tissue Sarcoma. Currently recruiting, targeting 51 participants across 1 site.

Detailed Summary

This phase II trial studies the side effects of hypofractionated radiation therapy in treating patients with soft tissue sarcomas prior to surgery. Hypofractionated radiation therapy delivers higher doses of radiation therapy over a shorter period of time and may kill more tumor cells and have fewer side effects.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRecurrent Adult Soft Tissue Sarcoma
CountriesUnited States
CollaboratorsRadiological Society of North America, Sarcoma Alliance for Research through Collaboration, Sarcoma Foundation of America, Tower Cancer Research Foundation

Timeline

N/ARecruiting
2016201720182019202020212022202320242025202620272028
First PostedMar 8, 2016
Enrollment StartFeb 3, 2016
Primary CompletionFeb 3, 2027
Study CompletionFeb 3, 2028
TodayJul 2, 2026
Enrollment to primary: 11 yearsPosted 10.3 years agoPrimary completion in 7 months

Interventions

Conventional Surgeryprocedure

Undergo surgery

Hypofractionated Radiation Therapyradiation

Undergo hypofractionated radiation therapy

Laboratory Biomarker Analysisother

Correlative studies

Questionnaire Administrationother

Ancillary studies