CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 677 enrolled
Drug / intervention
Laparoscopic cholecystectomy with Xenon light +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02702843
NCT02702843N/ACompleted

Efficacy Of Near Infrared Incisionless Fluorescent Cholangiography (NIFC) During Laparoscopic Cholecystectomy

The Cleveland Clinic·interventional·Posted Mar 9, 2016·Updated Nov 12, 2025

In Brief

A clinical study evaluating Laparoscopic cholecystectomy with Xenon light and Laparoscopic cholecystectomy (fluorescent cholangiography) for Cholecystitis and Cholelithiasis. Completed, enrolled 677 participants across 7 sites in 5 countries.

Detailed Summary

The Study is designed to compare the effectiveness of Near Infrared Fluorescence Cholangiography (NIFC) to standard white light imaging (WLI) in visualizing and identifying the main biliary and hepatic structures (Cystic Duct, Right Hepatic Duct, Common Hepatic Duct, Common Bile Duct, Cystic-CBD junction, Cystic-Gallbladder junction and any Accessory Ducts) during laparoscopic cholecystectomy. The aim is to demonstrate that NIFC performs better than standard white light (WLI) alone in visualizing and identifying extra-hepatobiliary structures (Cystic Duct, Right Hepatic Duct, Common Hepatic Duct, Common Bile Duct, Cystic-CBD junction, Cystic-Gallbladder junction, and any Accessory Ducts) before and after dissection during Laparoscopic Cholecystectomy (LC).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesArgentina, Germany, Italy, Japan, United States

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedMar 9, 2016
Enrollment StartApr 1, 2016
Primary CompletionDec 31, 2017
Study CompletionAug 31, 2018
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 10.3 years ago

Interventions

Laparoscopic cholecystectomy with Xenon lightprocedure

Standard laparoscopic cholecystectomy with white light

Laparoscopic cholecystectomy (fluorescent cholangiography)procedure

Laparoscopic cholecystectomy in infrared light after injection of indocyanine green pre-operatively.