CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 232 enrolled
Drug / intervention
bupivacaine liposome injectable suspension +1 moredrug
Likely dose
bupivacaine liposome injectable suspension 133 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02713178
NCT02713178Phase 3Completed

A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block With EXPAREL for Postsurgical Analgesia in Subjects Undergoing Total Knee Arthroplasty

Pacira Pharmaceuticals, Inc·interventional·Posted Mar 18, 2016·Updated Dec 1, 2020

In Brief

A Phase 3 clinical trial evaluating bupivacaine liposome injectable suspension and Placebo for Pain. Completed, enrolled 232 participants across 17 sites in 3 countries.

Detailed Summary

This is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study in 232 adult subjects undergoing primary unilateral TKA under general or spinal anesthesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain
CountriesBelgium, Denmark, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20162017201820192020202120222023202420252026
First PostedMar 18, 2016
Enrollment StartJun 3, 2016
Primary CompletionJun 30, 2017
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 10.3 years ago

Interventions

bupivacaine liposome injectable suspensiondrug

bupivacaine liposome injectable suspension 133 mg expanded with normal saline to 20 mL or 266 mg in 20 mL

Placebodrug

Normal saline.