CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 30 enrolled
Drug / intervention
Roux-en-Y Gastric Bypass +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02713555
NCT02713555N/ACompleted
CompareCT.gov

Effects of Hepatic Insulin Resistance on Type 2 Diabetes Mellitus in Morbidly Obese Subjects Following Roux-en-Y Gastric Bypass Surgery or Gastric Sleeve Surgery

University of Aarhus·interventional·Posted Mar 18, 2016·Updated Jul 6, 2021

In Brief

A clinical study evaluating Roux-en-Y Gastric Bypass and Gastric Sleeve for Diabetes Mellitus, Type 2 and Obesity. Completed, enrolled 30 participants across 1 site.

Detailed Summary

Roux-en-Y Gastric Bypass surgery (RYGB) ameliorates type 2 diabetes within days after surgery. Studies indicate that the gastric sleeve procedure has comparable effect on type 2 diabetes, but to what extent and how is not fully elucidated. This study investigates the effect of the surgeries on incretin levels, glucose effectiveness and hepatic insulin sensitivity.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDiabetes Mellitus, Type 2, Obesity
CountriesDenmark
CollaboratorsUniversity of Copenhagen

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedMar 18, 2016
Enrollment StartJul 1, 2016
Primary CompletionFeb 20, 2021
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 10.3 years ago

Interventions

Roux-en-Y Gastric Bypassprocedure

Roux-en-Y Gastric Bypass surgery entails the formation of a small gastric pouch and the division of the small intestine 60 cm from the duodenum. Formation of a gastrojejunal anastomosis with the distal segment and the formation of a jejuno-jejunal anastomosis 150 cm from the gastrojejunal anastomosis with the biliary segment.

Gastric Sleeveprocedure

Gastric Sleeve entails a vertical division of the stomach with a stapler.