CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 241 enrolled
Drug / intervention
Normal Saline +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02714023
NCT02714023N/ACompleted

Water And Saline Head-to-head In The Blinded Evaluation Study Trial

University of Missouri-Columbia·interventional·Posted Mar 21, 2016·Updated Oct 15, 2018

In Brief

A clinical study evaluating Normal Saline and Sterile Water for Acute Appendicitis and Abscess. Completed, enrolled 241 participants across 1 site.

Detailed Summary

Patients who are diagnosed with acute appendicitis consented and then randomized into two arms of the trial. In one arm, patients receive irrigation of the abdomen during surgery with normal saline, or salt water. In the other arm, patients receive irrigation of the abdomen during surgery with sterile water. Sometimes patients receive no irrigation if none is determined to be needed at the time of operation by the surgeon. We then followed patients after surgery for 30 days. The hypothesis of this study was that the use of sterile water as irrigation fluid during surgery in patients who have acute appendicitis will decrease the chance of a post-operative abscess or infection.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedMar 21, 2016
Enrollment StartOct 10, 2012
Primary CompletionSep 10, 2015
Study CompletionNov 29, 2017
TodayJul 2, 2026
Enrollment to primary: 2.9 yearsPosted 10.3 years ago

Interventions

Normal Salineprocedure

Intra-operative irrigation with normal saline

Sterile Waterprocedure

Intra-operative irrigation with sterile water