CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 60 enrolled
Drug / intervention
Tazarotene 0.1% gel plus clindamycin 1% gel +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02721173
NCT02721173Phase 4Completed
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Comparison of Safety and Efficacy of Tazarotene 0.1% Plus Clindamycin 1% Gel vs. Adapalene 0.1% Plus Clindamycin 1% Gel in the Treatment of Facial Acne Vulgaris: A Randomized Controlled Trial

All India Institute of Medical Sciences, Bhubaneswar·interventional·Posted Mar 29, 2016·Updated Jan 18, 2017

In Brief

A Phase 4 clinical trial evaluating Tazarotene 0.1% gel plus clindamycin 1% gel and Adapalene 0.1% gel plus clindamycin 1% gel for Acne Vulgaris. Completed, enrolled 60 participants across 1 site.

Detailed Summary

The combination therapy of retinoid and clindamycin for acne is preferred because it targets multiple areas of acne pathogenesis that could not be accomplished with monotherapy, thereby improving outcome. Literature review reveals that till date there is no published comparative study assessing safety and efficacy of tazarotene plus clindamycin and adapalene plus clindamycin. So the present study has been designed to compare these two combination therapy in acne vulgaris.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcne Vulgaris
CountriesIndia
Collaborators--

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedMar 29, 2016
Enrollment StartApr 1, 2016
Primary CompletionDec 1, 2016
Study CompletionJan 1, 2017
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 10.3 years ago

Interventions

Tazarotene 0.1% gel plus clindamycin 1% geldrug

Medications will be advised to apply once daily in the evening after facial cleansing. Clindamycin will be applied first and tazarotene will be applied 5-10 minutes later.

Adapalene 0.1% gel plus clindamycin 1% geldrug

Medications will be advised to apply once daily in the evening after facial cleansing. Clindamycin will be applied first and adapalene will be applied 5-10 minutes later.