At a glance
ClinicalIndex Comparison RecordN/ACompleted· 82 enrolled
Drug / intervention
home intravenous ertapenem +2 moredrug
Likely dose
Ertapenem (IV) or amoxicillin-clavulanate (oral); specific doses not statedAI-extracted
Key inclusion· 2
- ✓Age 4–17 years
- ✓Perforated acute appendicitis diagnosed at time of appendectomy
Key exclusion· 4
- ✕Known severe allergy to penicillin (anaphylaxis)
- ✕Prior severe side effects from ertapenem or amoxicillin-clavulanate
- ✕Pregnancy
- ✕Previous drainage procedure for abscess and/or fluid collection related to appendicitis
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Home Intravenous Versus Oral Antibiotics Following Appendectomy for Perforated Appendicitis in Children, a Randomized Controlled Trial
In Brief
A clinical study evaluating home intravenous ertapenem, home oral amoxicillin-clavulanate, and 1 other intervention for Perforated Appendicitis. Completed, enrolled 82 participants.
Detailed Summary
To compare the effect of a single-agent home intravenous (IV) versus oral antibiotic therapy on complication rates and resource utilization following appendectomy for perforated appendicitis
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPerforated Appendicitis
Countries--
Collaborators--
Timeline
N/ACompletedFinished
2011201220132014201520162017201820192020202120222023202420252026
Enrollment StartJan 2011
Primary CompletionNov 2013
First PostedMar 2016
TodayJul 2026
First PostedMar 31, 2016
Enrollment StartJan 1, 2011
Primary CompletionNov 1, 2013
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 10.3 years ago
Interventions
home intravenous ertapenemdrug
see arm description
home oral amoxicillin-clavulanatedrug
see arm description
peripheral inserted central Catheterdevice
All patients undergoing home intravenous ertapenem will require placement of peripheral inserted central Catheter (PICC) for home delivery of antibiotics.