CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 99 enrolled
Drug / intervention
Dexamethasone +1 moredrug
Likely dose
Dexamethasone oral (dose not specified); comparison arm receives second dose on day after ED discharge versus placeboAI-extracted
Key inclusion· 1
  • ✓History of asthma with at least two prior episodes of respiratory illness with wheezing treated with inhaled beta agonists
Key exclusion· 4
  • ✕Pregnancy
  • ✕Severe chronic cardiac, respiratory, neurological or neuromuscular disease
  • ✕Complete resolution of symptoms after one treatment of beta agonists
  • ✕Severe asthma symptoms defined by Pulmonary Index Score of 12 or greater

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02725008
NCT02725008Phase 3Completed
CompareCT.gov

A Randomized Double Blinded Placebo Controlled Trial of One Versus Two Doses of Oral Dexamethasone for the Treatment of Acute Asthma Exacerbation in the Pediatric Emergency Department (ED)

Geoffrey W Jara-Almonte·interventional·Posted Mar 31, 2016·Updated Feb 27, 2019

In Brief

A Phase 3 clinical trial evaluating Dexamethasone and placebo for Asthma. Completed, enrolled 99 participants across 1 site.

Detailed Summary

Comparing one versus two doses of oral dexamethasone for the treatment of asthma in the pediatric emergency department.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20162017201820192020202120222023202420252026
First PostedMar 31, 2016
Enrollment StartNov 1, 2015
Primary CompletionNov 1, 2017
TodayJul 2, 2026
Enrollment to primary: 2 yearsPosted 10.3 years ago

Interventions

Dexamethasonedrug

placebodrug

to be given to the experimental group on the day after discharge from the ED in lieu of the second dose of dexamethasone