CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 22,435 enrolled
Drug / intervention
Propofol +43 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02726620
NCT02726620N/ACompleted

Decision Support for Intraoperative Low Blood Pressure

Vanderbilt University Medical Center·interventional·Posted Apr 4, 2016·Updated May 16, 2019

In Brief

A clinical study evaluating Attending real-time decision support, In-room real-time decision support, and 42 other interventions for Hypotension. Completed, enrolled 22,435 participants across 1 site.

Detailed Summary

The purpose of this study is to determine whether a decision support system can improve the adherence to thresholds for low blood pressure by anesthesia providers, which in turn prevents their patients from having organ injury.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypotension
CountriesUnited States
CollaboratorsUMC Utrecht

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedApr 4, 2016
Enrollment StartJan 5, 2017
Primary CompletionDec 31, 2017
Study CompletionDec 29, 2018
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 10.2 years ago

Interventions

Attending real-time decision supportprocedure

Near real-time decision support elements will notify the attending anesthesiologists of a blood pressure drop below the threshold for intraoperative hypotension (mean arterial pressure below 60 mmHg). The notification is presented through the pager system. The page will also display the associated increased risk of organ injury due to organ ischemia.

In-room real-time decision supportprocedure

Near real-time decision support elements will notify the in-room anesthesia provider of a blood pressure drop below the threshold for intraoperative hypotension (mean arterial pressure below 60 mmHg). The notification is presented through the anesthesia information management system. The decision support system will display the associated increased risk of organ injury due to organ ischemia.

Attending feedback emailsprocedure

Attending anesthesiologists will be notified through email within 24 hours after the end of an anesthetic case, when the patient had an episode of intraoperative hypotension (mean arterial pressure below 60 mmHg or lower for a particular duration) that is associated with an increased risk of organ injury due to organ ischemia.

In-room provider feedback emailsprocedure

In-room anesthesia providers will be notified through email within 24 hours after the end of an anesthetic case, when the patient had an episode of intraoperative hypotension (mean arterial pressure below 60 mmHg or lower for a particular duration) that is associated with an increased risk of organ injury due to organ ischemia.

Anesthesia Information Management System (AIMS)device

The anesthesia electronic record keeping system

Perioperative Data Warehouse (PDW)device

The data warehouse that is used to gather perioperative data and create user reports. In this instance the PDW will be used to send the postoperative feedback emails.

General anesthesiaprocedure

Any anesthetic drugs that are used to induce general anesthesia above the level of sedation.

Pager systemdevice

The mobile pager system through which alerts can be sent

Central neuraxial anesthesiaprocedure

Regional anesthesia effectuated through the placement of local anesthetics around the nerves of the central nervous system, e.g. spinal anesthesia and epidural anesthesia.

Non-cardiac surgeryprocedure

Any surgical intervention that is not aimed at surgical correction of the heart

Propofoldrug

Anesthetic drug used to maintain general anesthesia

Sevofluranedrug

Anesthetic drug used to maintain general anesthesia

Desfluranedrug

Anesthetic drug used to maintain general anesthesia

Isofluranedrug

Anesthetic drug used to maintain general anesthesia

Ephedrinedrug

Cardiovascular drug used to treat intraoperative hypotension

Phenylephrinedrug

Cardiovascular drug used to treat intraoperative hypotension

Norepinephrinedrug

Cardiovascular drug used to treat intraoperative hypotension

Epinephrinedrug

Cardiovascular drug used to treat intraoperative hypotension

Dobutaminedrug

Cardiovascular drug used to treat intraoperative hypotension

Dopaminedrug

Cardiovascular drug used to treat intraoperative hypotension

Isoproterenoldrug

Cardiovascular drug used to treat intraoperative hypotension

Milrinonedrug

Cardiovascular drug used to treat intraoperative hypotension

Atropinedrug

Cardiovascular drugs used to treat intraoperative hypotension

Glycopyrrolatedrug

Cardiovascular drug used to treat intraoperative hypotension

Vasopressindrug

Cardiovascular drug used to treat intraoperative hypotension

Terlipressindrug

Cardiovascular drug used to treat intraoperative hypotension

Sodium Chloride 0.9%drug

Intravenous fluid used to treat intraoperative hypotension

Ringer's lactatedrug

Intravenous fluid used to treat intraoperative hypotension

Hydroxyethyl starch solutionsdrug

Intravenous fluid used to treat intraoperative hypotension

Fresh Frozen Plasmadrug

Intravenous fluid used to treat intraoperative hypotension

Packed Red Blood Cellsdrug

Intravenous fluid used to treat intraoperative hypotension

Albumin solutionsdrug

Intravenous fluid used to treat intraoperative hypotension

Plasma-Lytedrug

Intravenous fluid used to treat intraoperative hypotension

Lidocainedrug

Local anesthetic used for central neuraxial anesthesia.

Bupivacainedrug

Local anesthetic used for central neuraxial anesthesia.

Levobupivacainedrug

Local anesthetic used for central neuraxial anesthesia.

Ropivacainedrug

Local anesthetic used for central neuraxial anesthesia.

Mepivacainedrug

Local anesthetic used for central neuraxial anesthesia.

Tetracainedrug

Local anesthetic used for central neuraxial anesthesia.

Prilocainedrug

Local anesthetic used for central neuraxial anesthesia.

Procainedrug

Local anesthetic used for central neuraxial anesthesia.

Chloroprocainedrug

Local anesthetic used for central neuraxial anesthesia.

Benzocainedrug

Local anesthetic used for central neuraxial anesthesia.

Articainedrug

Local anesthetic used for central neuraxial anesthesia.