CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 3 enrolled
Drug / intervention
Eculizumabdrug
Likely dose
Eculizumab 1200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02727608
NCT02727608Phase 2Completed

Induction With Complement Inhibitor Eculizumab in Clinical Islet Transplantation

Uppsala University·interventional·Posted Apr 4, 2016·Updated Oct 4, 2018

In Brief

A Phase 2 clinical trial evaluating Eculizumab for Diabetes Mellitus. Completed, enrolled 3 participants across 1 site.

Detailed Summary

This is a dual centre, single arm, exploratory study of the possibility to use eculizumab (Soliris) to prevent/reduce destruction of islets of Langerhans after portal infusion of the islets in patients with diabetics accepted for islet transplant.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSweden
Collaborators--

Timeline

Phase 2CompletedFinished
20162017201820192020202120222023202420252026
First PostedApr 4, 2016
Enrollment StartMay 15, 2016
Primary CompletionMay 1, 2018
Study CompletionJun 1, 2018
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 10.2 years ago

Interventions

Eculizumabdrug

Intravenous infusion (1200 mg) over 35 minutes. Consecutive infusions (900 mg) on Days 1, 7 and 14.