CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 80 enrolled
Drug / intervention
Clonidinedrug
Likely dose
Clonidine 1 µg/kg plus 2% lidocaineAI-extracted
Key inclusion· 4
  • ✓Age 30–86 years
  • ✓Either gender
  • ✓ASA physical status I or II
  • ✓Cooperative patients undergoing cataract surgery by phacoemulsification
Key exclusion· 8
  • ✕Chronic clonidine therapy
  • ✕Current antihypertensive medication use
  • ✕Diabetes
  • ✕Glaucoma

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02733757
NCT02733757Phase 2Completed
CompareCT.gov

Effects of Clonidine Added to Lidocaine in Sub-Tenon's and Peribulbar Anesthesia: Assessments of Intraocular Pressure (IOP), Ocular Perfusion Pressure (OPP) and Ocular Pulse Amplitude (OPA)

Federal University of Minas Gerais·interventional·Posted Apr 11, 2016·Updated Aug 25, 2020

In Brief

A Phase 2 clinical trial evaluating Clonidine for Anesthesia. Completed, enrolled 80 participants.

Detailed Summary

Regional anesthesia in orbit can reduce ocular blood flow, increase in intraocular pressure (IOP) or the pharmacological action of local anesthetics. This study was conduced to evaluate the effects of clonidine added to lidocaine in IOP, ocular perfusion pressure (PPO) and ocular pulse amplitude (OPA) in patients undergoing cataract surgery under sub-Tenon's and peribulbar anesthesia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnesthesia
Countries--
CollaboratorsFederal University of Espirito Santo

Timeline

Phase 2CompletedFinished
20132014201520162017201820192020202120222023202420252026
First PostedApr 11, 2016
Enrollment StartMay 1, 2013
Primary CompletionOct 1, 2015
Study CompletionDec 1, 2015
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 10.2 years ago

Interventions

Clonidinedrug

Clonidine 1 µg/kg plus 2% lidocaine