At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Effect of Naltrexone and Bupropion Combination on Weight Loss and Smoking Cessation in Obese, Cigarette-smoking Patients With Schizophrenia
In Brief
A Phase 4 clinical trial evaluating Naltrexone, Placebo Naltrexone, and 2 other interventions for Obese and 2 related conditions. Completed, enrolled 22 participants.
Detailed Summary
The purpose of this research is to observe the efficacy of Naltrexone and Bupropion combination on weight loss and smoking cessation from baseline to week 24 compare to placebo.
Study Details
Timeline
Interventions
3 tablets（15mg） once per day in the first two weeks，then Naltrexone 5 tablets（25mg） once per day during the rest of the study.
Placebo Naltrexone created and masked by the pharmacy to be used as a control.
1 capsule（150mg） once per day in the first two weeks，then 2 capsules（300mg） once per day during the rest of the study.
Placebo Bupropion created and masked by the pharmacy to be used as a control.