CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 20 enrolled
Drug / intervention
Aspirindrug
Likely dose
Aspirin 20mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02741817
NCT02741817Phase 4Completed

WilL LOWer Dose Aspirin be More Effective Following ACS? (WILLOW-ACS)

Sheffield Teaching Hospitals NHS Foundation Trust·interventional·Posted Apr 18, 2016·Updated Mar 17, 2021

In Brief

A Phase 4 clinical trial evaluating Aspirin for Acute Coronary Syndrome. Completed, enrolled 20 participants across 1 site.

Detailed Summary

The study is going to compare two different doses of aspirin for the treatment of heart disease in combination with the anticlotting medication ticagrelor. One of these doses of aspirin, 75 milligrams (mg) once a day, is the current standard treatment dose of aspirin used to treat heart attacks and angina. The other, 20 mg twice a day, is lower than the standard but there is growing scientific evidence that, when given with ticagrelor, this might offer advantages over the usual dose.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited Kingdom
Collaborators--

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedApr 18, 2016
Enrollment StartJun 26, 2016
Primary CompletionApr 7, 2017
TodayJul 2, 2026
Enrollment to primary: 9 monthsPosted 10.2 years ago

Interventions

Aspirindrug

The intervention has been described previously in both arms individually. Group A will receive 20mg of soluble Aspirin and group B with 75mg of soluble Aspirin. As this is a crossover study, all patients will fall under both groups throughout the duration and be un-blinded.