CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 180 enrolled
Drug / intervention
metformin +1 moredrug
Likely dose
metformin 500 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02741960
NCT02741960Phase 4Completed

A Multicenter, Randomised, Double-blind Placebo Controlled Trial on the Efficacy and Safety of add-on Metformin to Conventional Immunosuppressants in Systemic Lupus Erythematosus

RenJi Hospital·interventional·Posted Apr 18, 2016·Updated Sep 17, 2019

In Brief

A Phase 4 clinical trial evaluating metformin and placebo for Systemic Lupus Erythematosus. Completed, enrolled 180 participants across 1 site.

Detailed Summary

This is a multicenter, randomised, double-blind placebo controlled trial on the efficacy and safety of add-on metformin to conventional immunosuppressants in systemic lupus erythematosus (SLE). The purpose of this study is to evaluate: 1) the effect of metformin on reducing disease flares; 2) the influence of metformin on corticosteroid sparing effect; 3) the influence of metformin on body mass index (BMI); 4) the safety of metformin.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesChina
Collaborators--

Timeline

Phase 4CompletedFinished
2017201820192020202120222023202420252026
First PostedApr 18, 2016
Enrollment StartMay 24, 2016
Primary CompletionDec 13, 2017
Study CompletionDec 7, 2018
TodayJul 2, 2026
Enrollment to primary: 1.6 yearsPosted 10.2 years ago

Interventions

metformindrug

500 mg metformin three times daily

placebodrug

500 mg placebo three times daily