At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase 1B, Multicenter, Randomized, Double-masked, Controlled Study to Evaluate the Efficacy and Safety of a Fixed Combination Bimatoprost/Timolol Ocular Insert Compared to Its Individual Components With Crossover to Timolol 0.5% in Subjects With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)
In Brief
A Phase 2 clinical trial evaluating Fixed Combination, Bimatoprost, and 3 other interventions for Open-Angle Glaucoma and Ocular Hypertension. Completed, enrolled 55 participants across 1 site.
Detailed Summary
The purpose of this study is to determine if a combination of two drugs (bimatoprost and timolol) delivered to the surface of the eye over 10 weeks is better at lowering intraocular pressure (IOP) than either of the drugs delivered alone.
Study Details
Timeline
Interventions
Continuous elution from the ocular insert.
Continuous elution from the ocular insert. This is an active control arm.
Continuous elution from the ocular insert. This is an active control arm.
One segment of placebo (no drug product)
0.5% timolol drops twice daily.