CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 959 enrolled
Drug / intervention
670G and 770G Insulin Pump +1 moredevice
Likely dose
670G and 770G Insulin Pumpfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02748018
NCT02748018N/ACompleted

Multi-center, Randomized, Parallel, Adaptive, Controlled Trial in Adult and Pediatric Patients With Type 1 Diabetes Using Hybrid Closed Loop System and Control (CSII, MDI and SAP) at Home

Medtronic MiniMed, Inc.·interventional·Posted Apr 22, 2016·Updated Aug 19, 2025

In Brief

A clinical study evaluating 670G and 770G Insulin Pump and Subject's Current Diabetes Therapy for Type 1 Diabetes. Completed, enrolled 959 participants across 36 sites in 9 countries.

Detailed Summary

The purpose of this study is to evaluate the safety and effectiveness of the Hybrid Closed Loop system (HCL) in adult and pediatric patients with type 1 diabetes in the home setting. A diverse population of patients with type 1 diabetes will be studied. The study population will have a large range for duration of diabetes and glycemic control, as measured by glycosylated hemoglobin (A1C). They will be enrolled in the study regardless of their prior diabetes regimen, including using Multiple Daily Injections (MDI), Continuous Subcutaneous Insulin Infusion (CSII) or Sensor-Augmented Pump therapy (SAP)

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsType 1 Diabetes
CountriesCanada, France, Germany, Italy, New Zealand, Spain, Sweden, United Kingdom, United States
Collaborators--

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedApr 22, 2016
Enrollment StartMay 25, 2017
Primary CompletionNov 1, 2023
TodayJul 2, 2026
Enrollment to primary: 6.4 yearsPosted 10.2 years ago

Interventions

670G and 770G Insulin Pumpdevice

Medtronic 670G and 770G Hybrid Closed Loop Systems

Subject's Current Diabetes Therapydevice

Subject will use current diabetes therapy: CSII (Continuous Subcutaneous Insulin Infusion), MDI (Multiple Daily Injections) or SAP (Sensor Augmented Pump).