CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 65 enrolled
Drug / intervention
300 ug FLSC vaccine +3 morebiological
Likely dose
300 ug FLSC vaccine 1.0 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02756208
NCT02756208Phase 1Completed

A Phase I Safety and Immunogenicity Trial of IHV01 in HIV-1 Uninfected Volunteers

University of Maryland, Baltimore·interventional·Posted Apr 29, 2016·Updated Dec 16, 2021

In Brief

A Phase 1 clinical trial evaluating 300 ug FLSC vaccine, 150 ug FLSC vaccine, and 2 other interventions for HIV Infection. Completed, enrolled 65 participants across 1 site.

Detailed Summary

This study is designed to evaluate the safety of the FLSC vaccine and will be a randomized, placebo-controlled, modified double-blinded dose escalation study in 60 healthy adult volunteers (Human Immunodeficiency Virus-1 uninfected).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHIV Infection
CountriesUnited States

Timeline

Phase 1CompletedFinished
20162017201820192020202120222023202420252026
First PostedApr 29, 2016
Enrollment StartNov 1, 2015
Primary CompletionJul 1, 2018
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 10.2 years ago

Interventions

300 ug FLSC vaccinebiological

FLSC vaccine 300 ug (1.0 mL) given by intramuscular injection into the arm on study Days 0, 28, 56, 168

150 ug FLSC vaccinebiological

FLSC vaccine 150 ug (0.5 mL) given by intramuscular injection into the arm on study Days 0, 28, 56, 168

75 ug FLSC vaccinebiological

FLSC vaccine 75 ug (0.25 mL) given by intramuscular injection into the arm on study Days 0, 28, 56, 168

Placebobiological

Placebo sterile saline (0.25 - 1.0 mL) given by intramuscular injection into the arm on study Days 0, 28, 56, 168