CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 19 enrolled
Drug / intervention
Brimonidine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02761174
NCT02761174Phase 4Completed

Topical Brimonidine Reduces IPL-induced Erythema Without Affecting Efficacy: a Randomized Controlled Trial in Patients With Facial Telangiectasias

Merete Haedersdal·interventional·Posted May 4, 2016·Updated Jan 5, 2018

In Brief

A Phase 4 clinical trial evaluating Brimonidine and IPL+air-cooling for Telangiectasias. Completed, enrolled 19 participants across 1 site.

Detailed Summary

The aim of the study is to investigate whether brimonidine cream can reduce IPL-induced inflammation in terms of redness, swelling and pain in patients with facial vascular lesions (telangiectasias). Furthermore, the effect of brimonidine cream on IPL-efficacy is evaluated one month after final IPL-treatment. The hypothesis is that brimonidine, which has been proved effective in reduction of symptomatic erythema in patients with rosacea, also may have the ability to reduce IPL-induced erythema. Since the potential reduction in erythema is caused by vasoconstriction, brimonidine may further reduce IPL-induced oedema and pain.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsTelangiectasias
CountriesDenmark

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 4, 2016
Enrollment StartMar 13, 2016
Primary CompletionJul 11, 2016
Study CompletionJan 13, 2017
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 10.2 years ago

Interventions

Brimonidinedrug

Patients receive brimonidine to half of their face, whereas the other half receives no treatment and thereby patients are their own control

IPL+air-coolingother

IPL+air-cooling are applied to the whole face and the control side thereby only receives IPL+air-cooling