At a glance
ClinicalIndex Comparison RecordN/ACompleted· 17 enrolled
Drug / intervention
Ketamine +1 moredrug
Likely dose
Ketamine 2 mg/kgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia Reconstitution of Consciousness and Cognition (Phase 2)
In Brief
A clinical study evaluating Ketamine and Electroconvulsive Therapy for Depression and 3 related conditions. Completed, enrolled 17 participants across 1 site.
Detailed Summary
This study is geared toward characterizing the recovery of brain activity and cognitive function following treatments of electroconvulsive therapy and ketamine general anesthesia.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepression, Delirium, Seizures, Cognitive Disorders
CountriesUnited States
CollaboratorsJames S McDonnell Foundation
Timeline
N/ACompletedFinished
20162017201820192020202120222023202420252026
Enrollment StartApr 2016
First PostedMay 2016
Primary CompletionSep 2019
TodayJul 2026
First PostedMay 4, 2016
Enrollment StartApr 1, 2016
Primary CompletionSep 11, 2019
TodayJul 2, 2026
Enrollment to primary: 3.4 yearsPosted 10.2 years ago
Interventions
Ketaminedrug
Ketamine will be used to induce general anesthesia with or without subsequent ECT. Within a single patient, the dose will remain consistent throughout the study and is estimated to be 2 mg/kg.
Electroconvulsive Therapyprocedure
Dose of the ECT charge will be determined during titration session prior to randomization.