CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 45 enrolled / 45 target
Drug / intervention
Placebo +2 moredrug
Likely dose
125 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02762032
NCT02762032Phase 1CompletedUpdate Overdue (0.4/mo)Completion was 90mo ago
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The Ability of an Oral Supplement to Improve Skin Microperfusion, Hydration, Elasticity, and Barrier Function

Ohio State University·interventional·Posted May 4, 2016·Updated Jun 25, 2026

In Brief

A Phase 1 clinical trial evaluating PrimaVie Herbal Supplement 125, PrimaVie Herbal Supplement 250, and 1 other intervention for Healthy. Completed, enrolled 45 participants across 3 sites.

Signals

Enrollment appears stalled

Detailed Summary

This study will demonstrate the ability of the oral supplement, PrimaVie® to improve skin microperfusion, hydration, elasticity and barrier function. 45 females will be enrolled in 1 of 3 arms where they will receive either 125 mg PrimaVie, 250 mg PrimaVie or placebo (control) to take twice daily for 14 weeks.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
CollaboratorsNatreon, Inc.

Timeline

Phase 1CompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 4, 2016
Enrollment StartFeb 20, 2016
Primary CompletionDec 1, 2018
Study CompletionDec 20, 2019
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 10.2 years ago

Arms & Interventions

Arm 1active_comparator

15 subjects will be randomized to receive PrimaVie Herbal Supplement 125 mg to take twice daily for 14 weeks.

Dietary Supplement: PrimaVie Herbal Supplement 125
Arm 2active_comparator

15 subjects will be randomized to receive PrimaVie Herbal Supplement 250 mg to take twice daily for 14 weeks.

Dietary Supplement: PrimaVie Herbal Supplement 250
Arm 3placebo_comparator

15 subjects will be randomized to receive placebo (control supplement) to take twice daily for 14 weeks.

Drug: Placebo

Interventions

PrimaVie Herbal Supplement 125dietary

125 mg to take BID for 14 weeks in Arm 1

PrimaVie Herbal Supplement 250dietary

250 mg to take BID for 14 weeks in Arm 2

Placebodrug

Placebo supplement to take BID for 14 weeks in Arm 3