CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 108 enrolled
Drug / intervention
Liposomal bupivacaine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02762071
NCT02762071N/ACompleted
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Liposomal Bupivacaine vs. Interscalene Nerve Block for Pain Control After Total Shoulder Arthroplasty: A Randomized Clinical Trial

Johns Hopkins University·interventional·Posted May 4, 2016·Updated Mar 30, 2020

In Brief

A clinical study evaluating Liposomal bupivacaine and Interscalene Nerve Block for Osteoarthritis and 3 related conditions. Completed, enrolled 108 participants across 2 sites.

Detailed Summary

This study will compare interscalene nerve block versus liposomal bupivacaine (Exparel) for pain control after total shoulder replacements. Each method will be assessed in terms of post operative pain scores, pain medication consumption, length of stay, complications (nerve injuries, hematomas, cardiac/respiratory events) and rate of readmission due to pain. The aims of this study will be achieved through a randomized controlled trial and cost-effectiveness analysis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis, Arthropathy, Shoulder Pain, Closed Fracture Proximal Humerus, Four Part
CountriesUnited States
CollaboratorsUniversity of Texas Southwestern Medical Center

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedMay 4, 2016
Enrollment StartApr 1, 2016
Primary CompletionApr 15, 2019
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 10.2 years ago

Interventions

Liposomal bupivacainedrug

Patients in this group will receive a periarticular injection containing liposomal bupivacaine during surgery. The injection will be administered by the surgeon.

Interscalene Nerve Blockdrug

Patients in this group will receive an interscalene nerve block containing the local anesthetic ropivacaine prior to surgery. The nerve block will be administered by a fellowship-trained anesthesiologist.