CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 720 enrolled
Drug / intervention
Migraine Prophylactic Therapy Only +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02764320
NCT02764320N/ACompleted
CompareCT.gov

Determining the Optimal Treatment Strategy for Patients Who Have Chronic Migraine With Medication Overuse

Mayo Clinic·interventional·Posted May 6, 2016·Updated Nov 12, 2021

In Brief

A clinical study evaluating Migraine Prophylactic Therapy Only and Discontinuation of Overused Medication for Migraine. Completed, enrolled 720 participants across 29 sites.

Detailed Summary

There are two commonly used treatment strategies for treating patients who have chronic migraine with medication overuse. This study will compare the outcomes amongst patients randomized to one of the two treatment strategies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMigraine
CountriesUnited States
CollaboratorsPatient-Centered Outcomes Research Institute

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedMay 6, 2016
Enrollment StartJan 9, 2017
Primary CompletionMar 31, 2021
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 10.2 years ago

Interventions

Migraine Prophylactic Therapy Onlyother

Start of new migraine preventive therapy or adjustment of current preventive therapy without immediate discontinuation of the overused medication(s)

Discontinuation of Overused Medicationother

Immediate discontinuation of the overused medication(s) and the start of new migraine preventive therapy or adjustment of current preventive therapy