CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 116 enrolled
Drug / intervention
Docetaxel +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT02766335
NCT02766335Phase 3Completed

A Phase II Study of MEDI4736 for Previously Treated Patients With Stage IV Squamous Cell Lung Cancer and No Matching Biomarkers (Lung-Map Sub-Study)

SWOG Cancer Research Network·interventional·Posted May 9, 2016·Updated May 25, 2023

In Brief

A Phase 3 clinical trial evaluating Docetaxel, Durvalumab, and 1 other intervention for Recurrent Squamous Cell Lung Carcinoma and Stage IV Squamous Cell Lung Carcinoma AJCC v7. Completed, enrolled 116 participants across 993 sites.

Detailed Summary

This phase II trial studies how well durvalumab works in treating patients with stage IV squamous cell lung cancer that has come back after previous treatment. This is a "non-match" sub-study that includes all screened patients not eligible for a biomarker-driven sub-study. Monoclonal antibodies, such as durvalumab, may be able to shrink tumors. Durvalumab may be effective in treating patients with squamous cell lung cancer.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 3CompletedFinished
201520162017201820192020202120222023202420252026
First PostedMay 9, 2016
Enrollment StartJul 31, 2014
Primary CompletionSep 1, 2018
Study CompletionSep 1, 2020
TodayJul 2, 2026
Enrollment to primary: 4.1 yearsPosted 10.1 years ago

Interventions

Docetaxeldrug

Given IV

Durvalumabbiological

Given IV

Laboratory Biomarker Analysisother

Correlative studies